Relationship Between Serum Lactate Dehydogenase Activity and Lactate Dehydogenase Isoenzymes Changes and Methomyl Toxicity in Rats PDF Free

Relationship Between Serum Lactate Dehydogenase Activity and Lactate Dehydogenase Isoenzymes Changes and Methomyl Toxicity in Rats PDF
By:Ornrat Lohitnavy
Published on 1997 by

Studies on the effects of methomyl, a highly toxic carbamate insecticide, in rats receiving a single dose and repeated doses orally were carried out. The rats treated with single doses of 3-7 mg/kg of methomyl showed significant increase in total lactate dehydrogenase (LDH) activity on day 1. The highest total LDH enzyme activity occurred in the rats receiving 7 mg/kg of methomyl on day 3 after dosing. Subsequently, the level of LDH activity declined to normal level on days 5 and 7 after dosing. These high LDH activities were concurrent with significantly increased LDH-3 and LDH-4 level. Both spleen weight and splenocyte viability were significantly reduced in rats treated with an acute dose of 6 and 8 mg/kg of methomyl on days 1 and 3. Splenotoxicity effect seen was protected by pretreatment with N-acetylcysteine (NAC). These results are discussed in terms of various mechanisms which might be involved. The author suggests that mechanisms how NAC which acts as a scavenger of the free radical generated by injured cells protect against methomyl toxicity should be further investigated.

This Book was ranked at 37 by Google Books for keyword relationship activities.

Book ID of Relationship Between Serum Lactate Dehydogenase Activity and Lactate Dehydogenase Isoenzymes Changes and Methomyl Toxicity in Rats's Books is Z4byvQEACAAJ, Book which was written byOrnrat Lohitnavyhave ETAG "gM8ll1Fko5g"

Book which was published by since 1997 have ISBNs, ISBN 13 Code is 9789746372497 and ISBN 10 Code is 9746372491

Reading Mode in Text Status is false and Reading Mode in Image Status is false

Book which have "216 Pages" is Printed at BOOK under CategoryLactate dehydrogenase

Book was written in en

eBook Version Availability Status at PDF is falseand in ePub is false

Book Preview

Download Relationship Between Serum Lactate Dehydogenase Activity and Lactate Dehydogenase Isoenzymes Changes and Methomyl Toxicity in Rats PDF Free

Download Relationship Between Serum Lactate Dehydogenase Activity and Lactate Dehydogenase Isoenzymes Changes and Methomyl Toxicity in Rats Books Free

Download Relationship Between Serum Lactate Dehydogenase Activity and Lactate Dehydogenase Isoenzymes Changes and Methomyl Toxicity in Rats Free

Download Relationship Between Serum Lactate Dehydogenase Activity and Lactate Dehydogenase Isoenzymes Changes and Methomyl Toxicity in Rats PDF

Download Relationship Between Serum Lactate Dehydogenase Activity and Lactate Dehydogenase Isoenzymes Changes and Methomyl Toxicity in Rats Books